Last edited by Virisar
Wednesday, May 6, 2020 | History

9 edition of Protective groups in organic synthesis. found in the catalog.

Protective groups in organic synthesis.

by Theodora W. Greene

  • 324 Want to read
  • 7 Currently reading

Published by Wiley in New York .
Written in English

    Subjects:
  • Organic compounds -- Synthesis.,
  • Protective groups (Chemistry)

  • Edition Notes

    ContributionsWuts, Peter G. M.
    Classifications
    LC ClassificationsQD262 .G665 1991
    The Physical Object
    Paginationxvi, 473 p. :
    Number of Pages473
    ID Numbers
    Open LibraryOL1884755M
    ISBN 100471623016
    LC Control Number90045708

    Protective Groups in Organic Synthesis | Peter G. M. Wuts Theodora W. Greene | download | B–OK. Download books for free. Find books. Protective Groups in Organic Synthesis Theodora W. Greene, Peter G. M. Wuts Reflecting the latest advances in protective group methodology, this Third Edition of the proven laboratory reference is expanded by more than 50%, providing readers with a comprehensive compendium of 1, of the most useful protective groups as well as 5,

    1. The Role of Protective Groups in Organic Synthesis 1. Properties of a Protective Group 1. Historical Development 2. Development of New Protective Groups 2. Selection of a Protective Group from This Book 4. Synthesis of Complex Substances: Two Examples (As used in the Synthesis of Himastatin and Palytoxin) of the Selection Introduction and. Protective Groups in Organic Synthesis by Wuts, Peter G. M.,Greene, Theodora W. and a great selection of related books, art and collectibles available now at Protective Groups Organic Synthesis - AbeBooks.

    Greene’s Protective Groups is a useful guide to the organic chemist, and the content is organized on the basis of the functional group to be protected (i.e., ethers, amides, phenols, phosphates, etc). Within each section, the organization goes from the simple protective /5(7). Protective Groups in Organic Synthesis, 3rd Edition Theodora W. Green (The Rowland Institute for Science) and Peter G. M. Wuts (Pharmacia and Upjohn Company). John Wiley & Sons, Inc., New York, NY. xxi + pp. × 23 cm. $ ISBN


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Protective groups in organic synthesis by Theodora W. Greene Download PDF EPUB FB2

Protective Groups in Organic Synthesis., Third Edition. Author (s): Theodora W. Greene Ph.D., Peter G. Wuts Ph.D., First published: 9 April Print ISBN: | Online ISBN: | DOI: / Copyright © by John Wiley & Sons, Inc.

The Fourth Edition of Greene's Protective Groups in Organic Synthesis continues to be an indispensable reference for controlling the reactivity of the most common functional groups during a synthetic sequence. This new edition incorporates the significant developments in the field since publication of the third edition inincluding.

For more than twenty-five years, Protective Groups in Organic Synthesis has been the definitive guide for organic chemists in designing synthetic routes. Now in its fourth edition, the text continues to be a uniquely comprehensive and an indispensable reference for both synthetic organic and medicinal chemists who want to control the reactivity of the most common functional groups during a synthetic sequence/5(22).

Greene’s Protective Groups is a useful guide to the organic chemist, and the content is organized on the basis of the functional group to be protected (i.e., ethers, amides, phenols, phosphates, etc).

Within each section, the organization goes from the simple protective groups Cited by: • Presents valuable material, on the application of protective groups in organic chemistry, that is not easily found by casual searching • Helps chemists to plan, investigate, and carry out organic syntheses in an efficient manner • Adds over new references to update since the publication of the last edition.

well-organized and reasonably priced. Along with March's Advanced Organic Chemistry, this book is a must have for any organic chemist. The most comprehensive text on protecting groups there is.

Much better than "Protecting Groups" by Phillip J. Kocienski Greene's Protective Groups in Organic Synthesis Protective Groups in Organic Synthesis GroupsFile Size: KB. Protective groups are organized by six major organic functional groups: hydroxyl, amino, carboxyl, carbonyl, sulfhydryl, and phosphate groups (the last new to this edition).

Also added in this edition are protection of the alkyne-CH, expanded coverage of protection of all groups, and many new enzymatic methods of protection and deprotection. Carbonyl protecting groups in Organic Synthesis. Protection of carbonyl groups: Acetals and Ketals – Removed by acid.

Normally, the cleavage of acyclic acetals is easier than of cyclic acetals. Acylals – Removed by Lewis acids.

Dithianes – Removed by metal salts or oxidizing agents. The Role of Protective Groups in Organic Synthesis Properties of a Protective Group, 1 Historical Development, 2 Development of New Protective Groups, 2 Selection of a Protective Group from This Book, 4 xi xiii XV xvii xix xxi 1 Synthesis of Complex Substances: Two Examples (As used in the Synthesis ofFile Size: 1MB.

A protecting group (PG) is a molecular framework that is introduced onto a specific functional group (FG) in a poly-functional molecule to block its reactivity under reaction conditions needed to make modifications elsewhere in the molecule.

PM 4. Qualities of a Good Protecting Group in Organic Synthesis. The Role of Protective Groups in Organic Synthesis 1 2. Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols 16 Ethers, 24 Esters, Protection for 1,2- and 1,3-Diols, 3.

Protection for Phenols and Catechols Protection for Phenols, Ethers, Silyl Ethers, Esters, Carbonates, Aryl Carbamates, Phosphinates,   The Fourth Edition of Greene's Protective Groups in Organic Synthesis continues to be an indispensable reference for controlling the reactivity of the most common functional groups during a synthetic sequence.

This new edition incorporates the significant developments in the field since publication of the third edition inincluding New protective groups such as the/5. Correspondingly, more protective groups have been devised for the protection of amino and imino groups than for any other functional group.

There are many reviews and books on the synthesis of pep tides but there has been no general survey of protective groups since my 1 own review in At that time the five main methods for the removal of. Greene's Protective Groups in Organic Synthesis $ Only 1 left in stock - order soon/5(22).

The Fourth Edition of Greenes Protective Groups in Organic Synthesis continues to be an indispensable reference for controlling the reactivity of the most common functional groups during a synthetic sequence.

This new edition incorporates the significant developments in the field since publication of the third edition inincluding. This book reveals the logic behind the described methods and discuss the mechanisms. I never expected I would want to own another protection/deprotection reference book in addition to Greene's "Protective groups in organic synthesis" and I was wrong.5/5(1).

The Fourth Edition of Greene's Protective Groups in Organic Synthesis continues to be an indispensable reference for controlling the reactivity of the most common functional groups during a synthetic sequence.

This new edition incorporates the significant developments in the field since publication of the third edition inincluding New protective groups such as the fluorous family.

A protective group must fulfill a number of requirements. It must react selectively in good yield to give a protected substrate that is stable to the projected reactions.

The protective group must be selectively removed in good yield by readily available, preferably nontoxic reagents that do not attack the regenerated functional group. The Fourth Edition of Greene's Protective Groups in Organic Synthesis continues to be an indispensable reference for controlling the reactivity of the most common functional groups during a synthetic sequence.

This new edition incorporates the significant developments in the field since publication of the third edition inincluding 5/5(1).

The Role of Protective Groups in Organic Synthesis. Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols. Protection for Phenols and Catechols.

Protection for the Carbonyl Group. Protection for the Carboxyl Group. Protection for the Thiol Group. Protection for the Amino Group.

Protection for the Alkyne-CH. Protection for the Phosphate Group. Greene’s Protective Groups in Organic Synthesis 5th Edition [スポンサーリンク] An indispensable reference for any practicing synthetic organic or medicinal chemist, this book continues the tradition of Greene’s as comprehensive in the overall scope of coverage, providing the most relevant and useful examples to illustrate each.Greene's Protective Groups in Organic Synthesis Peter G.

M. Wuts An indispensable reference for any practicing synthetic organic or medicinal chemist, this book continues the tradition of Greene’s as comprehensive in the overall scope of coverage, providing the most relevant and useful examples to illustrate each methodology.A frequent requirement in organic synthesis is the protection of one or more of the major functional groups - the hydroxyl, amino, carboxyl, carbonyl and sulfhydryl groups.

For these major functional groups, the book provides concise, comprehensive coverage of the most useful protective groups.